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Stem cell-based treatment of kidney diseases.


ABSTRACT:

Impact statement

Stem cells hold great promise in regenerative medicine. Pluripotent stem cells have been differentiated into kidney organoids to understand human kidney development and to dissect renal disease mechanisms. Meanwhile, recent studies have explored the treatment of kidney diseases using a variety of cells, including mesenchymal stem cells and renal derivatives. This mini-review discusses the diverse mechanisms underlying current renal disease treatment via stem cell therapy. We postulate that clinical applications of stem cell therapy for kidney diseases can be readily achieved in the near future.

SUBMITTER: Pan B 

PROVIDER: S-EPMC7268929 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Stem cell-based treatment of kidney diseases.

Pan Binbin B   Fan Guoping G  

Experimental biology and medicine (Maywood, N.J.) 20200411 10


<h4>Impact statement</h4>Stem cells hold great promise in regenerative medicine. Pluripotent stem cells have been differentiated into kidney organoids to understand human kidney development and to dissect renal disease mechanisms. Meanwhile, recent studies have explored the treatment of kidney diseases using a variety of cells, including mesenchymal stem cells and renal derivatives. This mini-review discusses the diverse mechanisms underlying current renal disease treatment via stem cell therapy  ...[more]

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