Ontology highlight
ABSTRACT:
SUBMITTER: Barnabas RV
PROVIDER: S-EPMC7268961 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Barnabas Ruanne V RV Brown Elizabeth E Bershteyn Anna A Miller R Scott RS Wener Mark M Celum Connie C Wald Anna A Chu Helen H Wesche David D Baeten Jared M JM
Trials 20200603 1
<h4>Objectives</h4>Primary Objective • To test the efficacy of Hydroxychloroquine (HCQ) (400 mg orally daily for 3 days then 200 mg orally daily for an additional 11 days, to complete 14 days) to prevent incident SARS-CoV-2 infection, compared to ascorbic acid among contacts of persons with SARS-CoV-2 infection Secondary objectives • To determine the safety and tolerability of HCQ as SARS-CoV-2 Post-exposure Prophylaxis (PEP) in adults • To test the efficacy of HCQ (400 mg orally daily for 3 day ...[more]