Unknown

Dataset Information

0

Efficacy of hydroxychloroquine for post-exposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among adults exposed to coronavirus disease (COVID-19): a structured summary of a study protocol for a randomised controlled trial.


ABSTRACT:

SUBMITTER: Barnabas RV 

PROVIDER: S-EPMC7268961 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Efficacy of hydroxychloroquine for post-exposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among adults exposed to coronavirus disease (COVID-19): a structured summary of a study protocol for a randomised controlled trial.

Barnabas Ruanne V RV   Brown Elizabeth E   Bershteyn Anna A   Miller R Scott RS   Wener Mark M   Celum Connie C   Wald Anna A   Chu Helen H   Wesche David D   Baeten Jared M JM  

Trials 20200603 1


<h4>Objectives</h4>Primary Objective • To test the efficacy of Hydroxychloroquine (HCQ) (400 mg orally daily for 3 days then 200 mg orally daily for an additional 11 days, to complete 14 days) to prevent incident SARS-CoV-2 infection, compared to ascorbic acid among contacts of persons with SARS-CoV-2 infection Secondary objectives • To determine the safety and tolerability of HCQ as SARS-CoV-2 Post-exposure Prophylaxis (PEP) in adults • To test the efficacy of HCQ (400 mg orally daily for 3 day  ...[more]

Similar Datasets

| S-EPMC7732017 | biostudies-literature
| S-EPMC1188015 | biostudies-literature
| S-EPMC9349740 | biostudies-literature
| S-EPMC7276957 | biostudies-literature
| S-EPMC7316578 | biostudies-literature