The Role of Ambient Particle Radioactivity in Inflammation and Endothelial Function in an Elderly Cohort.

ABSTRACT:

Background

The mechanisms by which exposure to particulate matter might increase risk of cardiovascular morbidity and mortality are not fully known. However, few existing studies have investigated the potential role of particle radioactivity. Naturally occurring radionuclides attach to particulate matter and continue to release ionizing radiation after inhalation and deposition in the lungs. We hypothesize that exposure to particle radioactivity increases biomarkers of inflammation.

Methods

Our repeated-measures study included 752 men in the greater Boston area. We estimated regional particle radioactivity as a daily spatial average of gross beta concentrations from five monitors in the study area. We used linear mixed-effects regression models to estimate short- and medium-

SUBMITTER: Blomberg AJ 

PROVIDER: S-EPMC7269805 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature