Reproducibility of EEG functional connectivity in Alzheimer's disease.

ABSTRACT:

Background

Although numerous electroencephalogram (EEG) studies have described differences in functional connectivity in Alzheimer's disease (AD) compared to healthy subjects, there is no general consensus on the methodology of estimating functional connectivity in AD. Inconsistent results are reported due to multiple methodological factors such as diagnostic criteria, small sample sizes and the use of functional connectivity measures sensitive to volume conduction. We aimed to investigate the reproducibility of the disease-associated effects described by commonly used functional connectivity measures with respect to the amyloid, tau and neurodegeneration (A/T/N) criteria.

Methods

Eyes-closed task-free 21-channel EEG was used from patients with probable AD and subjective cog

SUBMITTER: Briels CT 

PROVIDER: S-EPMC7271479 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature