The role of pubertal timing in the link between family history of alcohol use disorder and late adolescent substance use.

ABSTRACT:

Background

Youth who experience puberty earlier than their peers are at heightened risk for substance use during adolescence. However, little is known about whether pubertal timing exacerbates effects of relevant early risk factors, such as family substance use history, as predicted by the "accentuation hypothesis". Using longitudinal data from youth with and without a family history of alcohol use disorder (AUD FHx), we evaluated whether pubertal timing intensifies preexisting familial risk effects on late adolescent substance use.

Methods

Participants were 568 males and 245 females from the Michigan Longitudinal Study. Pubertal timing was indexed by fitting mixed-effects linear models to repeated measures of self-reported Tanner stage. Multilevel models then tested: (a) wh

SUBMITTER: Weigard AS 

PROVIDER: S-EPMC7271760 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature