G-OnRamp: Generating genome browsers to facilitate undergraduate-driven collaborative genome annotation.

ABSTRACT: Scientists are sequencing new genomes at an increasing rate with the goal of associating genome contents with phenotypic traits. After a new genome is sequenced and assembled, structural gene annotation is often the first step in analysis. Despite advances in computational gene prediction algorithms, most eukaryotic genomes still benefit from manual gene annotation. This requires access to good genome browsers to enable annotators to visualize and evaluate multiple lines of evidence (e.g., sequence similarity, RNA sequencing [RNA-Seq] results, gene predictions, repeats) and necessitates many volunteers to participate in the work. To address the technical barriers to creating genome browsers, the Genomics Education Partnership (GEP; https://gep.wustl.edu/) has partnered with the Galaxy Proj

SUBMITTER: Sargent L 

PROVIDER: S-EPMC7272004 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature