Toxicological study of various crude extracts of Hyoscyamus gallagheri native to Oman.

ABSTRACT: Cancer is considered a major health issue all over the world for its high morbidity and mortality. Naturally obtained anticancer compounds have comparatively less side-effects, thus it remains a major focus for research. Hyoscyamus gallagheri (H. gallagheri), is one of the plants which have a useful source of bioactive metabolites. The present study is based on preparing plant extracts from the aerial parts of the herbal drug H. gallagheri with various polarities, determining their cytotoxicity and isolating the major cytotoxic compound from the highest active extract. A methanol extract was prepared by the Soxhlet extraction method. Then, it was processed with solvents of increasing polarities. Later, the extracts were evaluated for their cytotoxic activity by brine s

SUBMITTER: Aboalola DM 

PROVIDER: S-EPMC7272497 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature