Capgras Delusion in Posterior Cortical Atrophy-A Quantitative Multimodal Imaging Single Case Study.

ABSTRACT: Although Alzheimer's disease presents homogeneous histopathology, it causes several clinical phenotypes depending on brain regions involved. Beside the most abundant memory variant, several atypical variants exist. Among them posterior cortical atrophy (PCA) is associated with severe visuospatial/visuoperceptual deficits in the absence of significant primary ocular disease. Here, we report for the first time a case of Capgras delusion-a delusional misidentification syndrome, where patients think that familiar persons are replaced by identical "doubles" or an impostor-in a patient with PCA. The 57-year-old female patient was diagnosed with PCA and developed Capgras delusion 8 years after first symptoms. The patient did not recognize her husband, misidentified him as a stranger, and perceive

SUBMITTER: Schroeter ML 

PROVIDER: S-EPMC7272572 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature