Metabolic Pathways Associated With Term Labor Induction Course in African American Women.

ABSTRACT:

Objectives

The purpose of this study was to evaluate differences in the metabolic pathways activated in late-pregnancy serum samples among African American women who went on to have term (≥37 weeks) labor induction requiring high total oxytocin doses to complete first-stage labor compared to those in similar women with low-oxytocin labor inductions.

Study design

Case-control study (N = 27 women with labor induction with successful cervical ripening: 13 requiring the highest total doses of synthetic oxytocin to progress from 4- to 10-cm cervical dilation and 14 requiring the lowest total doses) with groups balanced on parity and gestational age. Serum samples obtained between 24 and 30 weeks' gestation were analyzed using ultra-high-resolution metabolomics. Differentia

SUBMITTER: Carlson NS 

PROVIDER: S-EPMC7273804 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature