Biomarkers of sepsis: time for a reappraisal.

ABSTRACT:

Introduction

Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic functions. In a previous review, we identified 3370 references reporting on 178 different biomarkers related to sepsis. In the present review, we evaluate the progress in the research of sepsis biomarkers.

Methods

Using the same methodology as in our previous review, we searched the PubMed database from 2009 until September 2019 using the terms "Biomarker" AND "Sepsis." There were no restrictions by age or language, and all studies, clinical and experimental, were included.

Results

We retrieved a total of 5367 new references since our previous review. We identified 258 biomarkers, 80 of which were new compared to our previous list. The majority of biomarkers have been evaluated i

SUBMITTER: Pierrakos C 

PROVIDER: S-EPMC7273821 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature