Trends in mental health clinical research: Characterizing the ClinicalTrials.gov registry from 2007-2018.

ABSTRACT: While the epidemiologic burden of mental health disorders in the United States has been well described over the past decade, we know relatively little about trends in how these disorders are being studied through clinical research. We examined all US interventional mental health trials submitted to ClinicalTrials.gov between October 1, 2007 and April 30, 2018 to identify trends in trial characteristics, comparisons with non-mental health trials, and trial attributes associated with discontinuation and results reporting. International data were excluded to minimize potential confounding. Over this period, mental health and non-mental health trials grew at similar rates, though Industry and US government-funded trials declined and academic medical center/hospital/other (AMC/Hosp/Oth) funded

SUBMITTER: Wortzel JR 

PROVIDER: S-EPMC7274444 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature