Quality of life across domains among individuals with treatment-resistant depression.

ABSTRACT:

Background

Treatment-resistant depression affects millions of people worldwide and is a leading cause of disability and suicide. Studies of treatment-resistant depression outcomes have traditionally focused on depressive symptoms and functional impairment. Quality of life (QoL) has not been well described. We aimed to measure QoL in individuals with treatment-resistant depression and to determine how QoL was related to traditional measures of symptoms and social functioning.

Methods

We used a reliable, cross-culturally validated questionnaire, the abbreviated World Health Organization Quality of Life scale (WHOQOL-BREF), to prospectively measure QoL in 79 patients with treatment-resistant depression who were referred for electroconvulsive therapy at a United States tertiary-

SUBMITTER: Lex H 

PROVIDER: S-EPMC7274522 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature