Management of Coronary Disease in Patients with Advanced Kidney Disease.

ABSTRACT:

Background

Clinical trials that have assessed the effect of revascularization in patients with stable coronary disease have routinely excluded those with advanced chronic kidney disease.

Methods

We randomly assigned 777 patients with advanced kidney disease and moderate or severe ischemia on stress testing to be treated with an initial invasive strategy consisting of coronary angiography and revascularization (if appropriate) added to medical therapy or an initial conservative strategy consisting of medical therapy alone and angiography reserved for those in whom medical therapy had failed. The primary outcome was a composite of death or nonfatal myocardial infarction. A key secondary outcome was a composite of death, nonfatal myocardial infarction, or hospitalization for un

SUBMITTER: Bangalore S 

PROVIDER: S-EPMC7274537 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature