Outcomes of Hydroxychloroquine Usage in United States Veterans Hospitalized with COVID-19.

ABSTRACT:

Background

Despite limited and conflicting evidence, hydroxychloroquine, alone or in combination with azithromycin, is widely used in COVID-19 therapy.

Methods

We performed a retrospective study of electronic health records of patients hospitalized with confirmed SARS-CoV-2 infection in US Veterans Health Administration medical centers between March 9, 2020 and April 29, 2020. Patients hospitalized within 24 h of diagnosis were classified based on their exposure to hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) or no HC as treatments. The primary outcomes were mortality and use of mechanical ventilation.

Findings

A total of 807 patients were evaluated. Compared to the no HC group, after propensity score adjustment for clinical characteristics, the risk of

SUBMITTER: Magagnoli J 

PROVIDER: S-EPMC7274588 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature