Percutaneous Application of Galvanic Current in Rodents Reverses Signs of Myofascial Trigger Points.

ABSTRACT: An increase in the spontaneous release of acetylcholine (ACh) at the motor endplate is directly related to the generation of myofascial trigger points (MTrPs). In this study, percutaneous electric fields were applied to an animal model of MTrPs with high levels of spontaneous ACh release. All experiments were performed on Swiss mice and Sprague Dawley rats. For evaluating the spontaneous neurotransmission, intracellular recordings were performed, and the frequency of miniature endplate potentials was evaluated. Electromyographic recordings were also conducted to evaluate the endplate noise. Finally, the number and strength of local twitch responses (LTR) were evaluated using ultrasound recordings. The protocols used for the electric currents were 0.4 mA for five seconds and four repetition

SUBMITTER: Margalef R 

PROVIDER: S-EPMC7275229 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature