Prevalence of co-existing autoimmune disease in juvenile idiopathic arthritis: a cross-sectional study.

ABSTRACT:

Background

Many autoimmune diseases share common pathogenic mechanisms, cytokine pathways and systemic inflammatory cascades; however, large studies quantifying the co-existence of autoimmune diseases in patients with juvenile idiopathic arthritis (JIA) have not been conducted.

Methods

We performed a cross-sectional study using two United States administrative healthcare claims databases (Truven Health MarketScan® Commercial Database and IMS PharMetrics database) to screen for the prevalence of multiple autoimmune diseases in patients with JIA and in a control group with attention deficit hyperactivity disorder (ADHD). Patients with a diagnosis code for JIA or ADHD between January 1, 2006 and September 30, 2017 were separated into two age cohorts (< 18 and ≥ 18 years) and ma

SUBMITTER: Simon TA 

PROVIDER: S-EPMC7275412 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature