Saccharomyces cerevisiae nutrient signaling pathways show an unexpected early activation pattern during winemaking.

ABSTRACT:

Background

Saccharomyces cerevisiae wine strains can develop stuck or sluggish fermentations when nutrients are scarce or suboptimal. Nutrient sensing and signaling pathways, such as PKA, TORC1 and Snf1, work coordinately to adapt growth and metabolism to the amount and balance of the different nutrients in the medium. This has been exhaustively studied in laboratory strains of S. cerevisiae and laboratory media, but much less under industrial conditions.

Results

Inhibitors of such pathways, like rapamycin or 2-deoxyglucose, failed to discriminate between commercial wine yeast strains with different nutritional requirements, but evidenced genetic variability among industrial isolates, and between laboratory and commercial strains. Most signaling pathways involve events of pr

SUBMITTER: Vallejo B 

PROVIDER: S-EPMC7275465 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature