Quality use of medicines in patients with chronic kidney disease.

ABSTRACT:

Background

Chronic kidney disease (CKD) affects drug elimination and patients with CKD require appropriate adjustment of renally cleared medications to ensure safe and effective pharmacotherapy. The main objective of this study was to determine the extent of potentially inappropriate prescribing (PIP; defined as the use of a contraindicated medication or inappropriately high dose according to the kidney function) of renally-cleared medications commonly prescribed in Australian primary care, based on two measures of kidney function. A secondary aim was to assess agreement between the two measures.

Methods

Retrospective analysis of routinely collected de-identified Australian general practice patient data (NPS MedicineWise MedicineInsight from January 1, 2013, to June 1, 2016;

SUBMITTER: Castelino RL 

PROVIDER: S-EPMC7275522 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature