Recommendations for fluid management of adults with sepsis in sub-Saharan Africa: a systematic review of guidelines.

ABSTRACT:

Background

Sepsis guidelines are widely used in high-income countries and intravenous fluids are an important supportive treatment modality. However, fluids have been harmful in intervention trials in low-income countries, most notably in sub-Saharan Africa. We assessed the relevance, quality and applicability of available guidelines for the fluid management of adult patients with sepsis in this region.

Methods

We identified sepsis guidelines by systematic review with broad search terms, duplicate screening and data extraction. We included peer-reviewed publications with explicit relevance to sepsis and fluid therapy. We excluded those designed exclusively for specific aetiologies of sepsis, for limited geographic locations, or for non-adult populations. We used the AGREE II

SUBMITTER: Silberberg B 

PROVIDER: S-EPMC7275525 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature