Patient familiarity with, understanding of, and preferences for clinical trial endpoints and terminology.

ABSTRACT:

Background

Although there is increased attention to designing and explaining clinical trials in ways that are clinically meaningful for patients, there is limited information on patient preferences, understanding, and perceptions of this content.

Methods

Maximum difference scaling (MaxDiff) methodology was used to develop a survey for assessing patients' understanding of 19 clinical terms and perceived importance of 9 endpoint surrogate phrases used in clinical trials and consent forms. The survey was administered electronically to individuals with metastatic breast cancer affiliated with the Metastatic Breast Cancer Alliance. Analyses were performed using Bayesian P values with statistical software.

Results

Among 503 respondents, 77% had a college degree, 70% were di

SUBMITTER: von Itzstein MS 

PROVIDER: S-EPMC7276207 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature