Microneedle Array: Applications, Recent Advances, and Clinical Pertinence in Transdermal Drug Delivery.

ABSTRACT: Drug delivery through the skin by transdermal patches has a long history. Subsequent growth of transdermal science proved prominent utility of transdermal systems meant for passive diffusion of the drug. It was followed by the development of iontophoresis- and sonophoresis-based transdermal delivery systems. Microneedle array has now caught attention of the investigators owing to its immense utility in transdermal delivery of very large molecules with ionic and hydrophilic nature. In this technical note, we present the current scenario, applications, and recent advances in microneedle array-based delivery of the most critical molecules through the skin. The application of microneedle has widely been investigated, and these technologies are being developed for the delivery of bio-therapeuti

SUBMITTER: Halder J 

PROVIDER: S-EPMC7276250 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature