Body mass index and risk of upper gastrointestinal cancer: A 30-year follow-up of the Linxian dysplasia nutrition intervention trial cohort.

ABSTRACT:

Background

Although a number of previous studies have noted the association between body mass index (BMI) and upper gastrointestinal (UGI) cancer risk, little evidence exists in the Chinese esophageal squamous dysplasia population. This prospective study investigated the association between BMI and UGI cancer risk in the Linxian Dysplasia Nutrition Intervention Trial (NIT) cohort.

Methods

A total of 3298 participants were included in the final analysis. Asian-specific BMI cut-offs were used to define BMI subgroups: underweight <18.5 kg/m², normal ≥18.5 to <24 kg/m² and overweight or obese ≥24 kg/m². Hazard ratios (HRs) and 95 % confidence intervals (95 %CIs) were estimated using the Cox proportional hazard model.

Results

During over 30

SUBMITTER: Zhang S 

PROVIDER: S-EPMC7276490 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature