The effects of repetitive transcranial magnetic stimulation on cue-induced craving in male patients with heroin use disorder.

ABSTRACT:

Background

Craving is a central feature of addiction. Early evidence suggests that repetitive transcranial magnetic stimulation is effective in reducing cue induced craving for patients with opioid use disorder (OUD). However, trials in large populations of patients with OUDs are lacking.

Methods

We randomly assigned 118 male heroin patients into three groups (i.e., 10 Hz rTMS, 1 Hz rTMS and a wait-list control group) from two addiction rehabilitation centers. rTMS was applied to the left dorsolateral prefrontal cortex (DLPFC) for 20 daily consecutive sessions.

Findings

Results showed that 10 Hz rTMS and 1 Hz rTMS were both effective in reducing cue-induced craving scores in heroin users when compared to the wait list group. The treatment effects lasted for up to 60 d

SUBMITTER: Liu X 

PROVIDER: S-EPMC7276507 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature