Genomic epidemiology and population structure of Neisseria gonorrhoeae in Norway, 2016-2017.

ABSTRACT: This study presents the nationwide epidemiology of Neisseria gonorrhoeae, using whole-genome sequencing of all culture-positive cases, which comprise roughly 40 % of all cases of gonorrhea reported in Norway from 2016 to 2017. Isolates were assigned to sequence types and Bayesian analysis clusters and variation in genes coding for antibiotic resistance was linked to phenotypic resistance data. The study also included isolates taken from the same patients from different anatomical sites at one or more time points. Comparing these isolates allows for observation of patterns of infections, i.e. multiple reinfections of genetically related clones vs. reinfections of genetically distant clones, and quantification of the genomic variation of closely related isolates from samples taken fro

SUBMITTER: Alfsnes K 

PROVIDER: S-EPMC7276708 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature