Bacteriophage Therapy for Critical Infections Related to Cardiothoracic Surgery.

ABSTRACT: (1) Objective: Bacterial resistance to conventional antibiotic therapy is an increasingly significant worldwide challenge to human health. The objective is to evaluate whether bacteriophage therapy could complement or be a viable alternative to conventional antibiotic therapy in critical cases of bacterial infection related to cardiothoracic surgery. (2) Methods: Since September 2015, eight patients with multi-drug resistant or especially recalcitrant Staphylococcus aureus, Enterococcus faecium, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli infections were treated with bacteriophage preparations as a therapy of last resort according to Article 37 of the Declaration of Helsinki. Patients had infections associated with immunosuppressio

SUBMITTER: Rubalskii E 

PROVIDER: S-EPMC7277081 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature