[BUB1 gene is highly expressed in gastric cancer:analysis based on Oncomine database and bioinformatics].

ABSTRACT:

Objective

To investigate the expression of BUB1 gene in gastric cancer.

Methods

Oncomine, GEPIA, BioGPS and Kaplan-Meier Plotter databases were used to analyze the difference of BUB1 gene expression between gastric cancer tissue and normal gastric tissue. The association of BUB1 expression level with the prognosis of gastric cancer patients was also analyzed. The Cancer Cell Line Encyclopedia (CCLE) was explored to analyze the expression of BUB1 in T cells and B cells in gastric cancer patients, and the String database was used to generate the network map of BUB1-related proteins and functional annotation of gene ontology (GO). The related pathways of KEGG were analyzed. Tumor immune assessment resource (TIMER) database was used to analyze the expression of BUB1 in immune in

SUBMITTER: Li X 

PROVIDER: S-EPMC7277308 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature