Genetic Diversity and Ancestral Study for Korean Native Pigs Using 60K SNP Chip.

ABSTRACT: The Korean native pig (KNP; Sus scrofa coreanus) is an indigenous porcine breed in South Korea considered as a valuable but dwindling genetic resource. Studies using diverse methodologies and genetic markers suggest that this population originated from the Manchu province of Northeastern China and migrated approximately 3000 years ago into the Korean peninsula. This study aimed to verify those findings by performing diversity and ancestral analyses using the 60K single-nucleotide polymorphism (SNP) BeadChip on 891 pigs of 47 breeds worldwide. We also performed principal component analysis (PCA), ancestry analyses, phylogenetic tree analysis using SNPhylo, and linkage disequilibrium analysis. Furthermore, we generated heatmap, obtained Nei's genetic distance and FST values, and explored the

SUBMITTER: Lee SH 

PROVIDER: S-EPMC7277343 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature