Evolutionary analysis of genes coding for Cysteine-RIch Secretory Proteins (CRISPs) in mammals.

ABSTRACT:

Background

Cysteine-RIch Secretory Proteins (CRISP) are expressed in the reproductive tract of mammalian males and are involved in fertilization and related processes. Due to their important role in sperm performance and sperm-egg interaction, these genes are likely to be exposed to strong selective pressures, including postcopulatory sexual selection and/or male-female coevolution. We here perform a comparative evolutionary analysis of Crisp genes in mammals. Currently, the nomenclature of CRISP genes is confusing, as a consequence of discrepancies between assignments of orthologs, particularly due to numbering of CRISP genes. This may generate problems when performing comparative evolutionary analyses of mammalian clades and species. To avoid such problems, we first carried out a

SUBMITTER: Arevalo L 

PROVIDER: S-EPMC7278046 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature