Current practice in analysing and reporting binary outcome data-a review of randomised controlled trial reports.

ABSTRACT:

Background

Randomised controlled trials (RCTs) need to be reported so that their results can be unambiguously and robustly interpreted. Binary outcomes yield unique challenges, as different analytical approaches may produce relative, absolute, or no treatment effects, and results may be particularly sensitive to the assumptions made about missing data. This review of recently published RCTs aimed to identify the methods used to analyse binary primary outcomes, how missing data were handled, and how the results were reported.

Methods

Systematic review of reports of RCTs published in January 2019 that included a binary primary outcome measure. We identified potentially eligible English language papers on PubMed, without restricting by journal or medical research area. Papers r

SUBMITTER: Rombach I 

PROVIDER: S-EPMC7278160 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature