Antirhea borbonica Aqueous Extract Protects Albumin and Erythrocytes from Glycoxidative Damages.

ABSTRACT: Diabetes constitutes a major health problem associated with severe complications. In hyperglycemic conditions, chronically increased oxidation and glycation of circulating components lead to advanced glycation end-products (AGEs) formation, a key contributor in diabetes complication progression. In line with literature documenting the beneficial properties of herbal teas, this study evaluates the antioxidant/glycant properties of Antirhea borbonica (Ab). Ab aqueous extract effects were tested on human albumin or erythrocytes submitted to methyl glyoxal-mediated glycoxidative damages. By using mass spectrometry, Ab aqueous extracts revealed to be rich in polyphenols. All tested biomarkers of oxidation and glycation, such as AGE, ketoamine, oxidized thiol groups, were decreased in albumin wh

SUBMITTER: Delveaux J 

PROVIDER: S-EPMC7278591 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature