Adipokines and Obesity. Potential Link to Metabolic Disorders and Chronic Complications.

ABSTRACT: The World Health Organization (WHO) has recognized obesity as one of the top ten threats to human health. It is estimated that the number of obese and overweight people worldwide exceeds the number of those who are undernourished. Obesity is not only a state of abnormally increased adipose tissue in the body, but also of increased release of biologically active adipokines. Adipokines released into the circulating blood, due to their specific receptors on the surface of target cells, act as classic hormones affecting the metabolism of tissues and organs. What is more, adipokines and cytokines may decrease the insulin sensitivity of tissues and induce inflammation and development of chronic complications. Certainly, it can be stated that in an era of a global obesity pandemic, adipokines may

SUBMITTER: Zorena K 

PROVIDER: S-EPMC7278967 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature