Effects of Baseline Thrombocytopenia and Platelet Decrease Following Renal Replacement Therapy Initiation in Patients With Severe Acute Kidney Injury.

ABSTRACT:

Objectives

Thrombocytopenia is common in critically ill patients with severe acute kidney injury and may be worsened by the use of renal replacement therapy. In this study, we evaluate the effects of renal replacement therapy on subsequent platelet values, the prognostic significance of a decrease in platelets, and potential risk factors for platelet decreases.

Design

Post hoc analysis of the Acute Renal Failure Trial Network Study.

Setting

The Acute Renal Failure Trial Network study was a multicenter, prospective, randomized, parallel-group trial of two strategies for renal replacement therapy in critically ill patients with acute kidney injury conducted between November 2003 and July 2007 at 27 Veterans Affairs and university-affiliated medical centers.

Subjects<

SUBMITTER: Griffin BR 

PROVIDER: S-EPMC7279613 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature