Effect of red blood cell transfusion on the development of retinopathy of prematurity: A systematic review and meta-analysis.

ABSTRACT:

Background

The effect of red blood cell (RBC) transfusion on retinopathy of prematurity (ROP) is difficult to establish, because ROP may also be influenced by other factors. Therefore, we carried out a systematic review and meta-analysis to explore the relationship between RBC transfusion and the development of ROP.

Methods

The PubMed, Embase, Cochrane Library and Web of Science databases were searched from their inception to September 1, 2019. Observational studies that reported the relationship between RBC transfusion and ROP after adjusting for other potential risk factors were included. The combined result was analyzed by a random effect model. Heterogeneity and publication bias were tested, and sensitivity analysis was performed.

Results

Of the 2628 identified re

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC7279893 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature