Self-assembled small molecule natural product gel for drug delivery: a breakthrough in new application of small molecule natural products.

ABSTRACT: Natural products, as a gift of nature to humanity, have long been used as drugs or pharmacological actives to help people cure various diseases. Yet we still know comparatively little about their ability to be materials. In recent years, some small molecule natural products isolated from traditional Chinese medicines have been found to have new features, namely, self-assembly to form gels (i.e., natural product gels, NPG). However, the application development of these natural products is seriously lacking, which greatly weakens their practical value and delays the maturity of the field. Here, a series of self-assembled triterpenoid natural products are used as materials (gel scaffolds) to construct drug delivery systems. Surprisingly, these NPG not only exhibit the excellent self-he

SUBMITTER: Zhi K 

PROVIDER: S-EPMC7280148 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature