Microtube Array Membrane (MTAM)-Based Encapsulated Cell Therapy for Cancer Treatment.

ABSTRACT: The treatment of cancer has evolved significantly in recent years with a strong focus on immunotherapy. Encapsulated Cell Therapy (ECT) for immunotherapy-based anti-cancer treatment is a unique niche within this landscape, where molecules such as signaling factors and antibodies produced from cells are encapsulated within a vehicle, with a host amount of benefits in terms of treatment efficacy and reduced side effects. However, traditional ECTs generally lie in two extremes; either a macro scale vehicle is utilized, resulting in a retrievable system but with limited diffusion and surface area, or a micro scale vehicle is utilized, resulting in a system that has excellent diffusion and surface area but is unretrievable in the event of side effects occurring, which greatly compromises the bi

SUBMITTER: Chew CH 

PROVIDER: S-EPMC7281484 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature