Impacts of glycemic variability on the relationship between glucose management indicator from iPro^™2 and laboratory hemoglobin A1c in adult patients with type 1 diabetes mellitus.

ABSTRACT:

Aims

Our aim was to investigate the impact of glycemic variability (GV) on the relationship between glucose management indicator (GMI) and laboratory glycated hemoglobin A1c (HbA1c).

Methods

Adult patients with type 1 diabetes mellitus (T1D) were enrolled from five hospitals in China. All subjects wore the iPro^™2 system for 14 days before HbA1c was measured at baseline, 3 months and 6 months. Data derived from iPro^™2 sensor was used to calculate GMI and GV parameters [standard deviation (SD), glucose coefficient of variation (CV), and mean amplitude of glycemic excursions (MAGE)]. Differences between GMI and laboratory HbA1c were assessed by the absolute value of the hemoglobin glycation index (HGI).

Results

A total of 91 sensor data and correspo

SUBMITTER: Liu H 

PROVIDER: S-EPMC7281639 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature