Stem Cell Clinical Trials in Spinal Cord Injury: A Brief Review of Studies in the United States.

ABSTRACT: Although many therapeutic approaches have been attempted to treat spinal cord injury, cellular transplantation offers the greatest promise in reconstituting the architecture of the damaged cord. A literature review was conducted to search for clinical trials investigating stem cells as treatment for spinal cord injury in the United States. Overall, eight studies met inclusion criteria. Of the included studies, four were identified as being terminated, suspended, or not yet recruiting. Two studies were identified as currently recruiting, including one phase one trial evaluating stereotactic injections of human spinal cord-derived neural stem cells in patients with chronic spinal cord injuries, and one trial of transplantation of autologous bone marrow derived stem cells via paraspinal injec

SUBMITTER: Platt A 

PROVIDER: S-EPMC7281746 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature