Association of [¹H]-MRS quantified liver fat content with glucose metabolism status.

ABSTRACT:

Background

Previous literatures have implied that the liver fat deposition plays a crucial role in the development and progression of insulin resistance. In the present study, we aimed to investigate the association of liver fat content (LFC) with glucose metabolism status in the population of newly diagnosed type 2 diabetes mellitus (nT2DM), prediabetes mellitus (PDM) and normal controls (NC), and assessing if the LFC could as an indicator for the prediction of T2DM.

Methods

A total of 242 subjects (including 141 nT2DM patients, 48 PDM subjects and 53 NC) were enrolled. The levels of LFC were quantified by using the proton magnetic resonance spectroscopy ([¹H]-MRS) technique. Clinical and laboratory parameters of study subjects were collected by medical records a

SUBMITTER: Wang YS 

PROVIDER: S-EPMC7282165 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature