Eosinophil count and mortality risk in incident hemodialysis patients.

ABSTRACT: BACKGROUND:Eosinophils are traditionally known as moderators of allergic reactions; however, they have now emerged as one of the principal immune-regulating cells as well as predictors of vascular disease and mortality in the general population. Although eosinophilia has been demonstrated in hemodialysis (HD) patients, associations of eosinophil count (EOC) and its changes with mortality in HD patients are still unknown. METHODS:In 107 506 incident HD patients treated by a large dialysis organization during 2007-11, we examined the relationships of baseline and time-varying EOC and its changes (ΔEOC) over the first 3 months with all-cause mortality using Cox proportional hazards models with three levels of hierarchical adjustment. RESULTS:Baseline median EOC was 231 (interquartile range 15

SUBMITTER: Kang DH 

PROVIDER: S-EPMC7282827 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature