The Link Between Structural and Functional Brain Abnormalities in Depression: A Systematic Review of Multimodal Neuroimaging Studies.

ABSTRACT:

Background

Adequate and timely identification of depression is essential to improve patient care. A potential method to achieve this is by using neuroimaging. Many neuroimaging studies have revealed widespread abnormalities in brain structure and function in patients with depression, but in most studies only single neuroimaging modalities were used. Links between abnormalities in brain structure and function need to be therefore further explored in order to define diagnostic and therapeutic applications.

Methods

A systematic literature review according to preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines was conducted.

Results

Out of 2,516 articles, only 14 studies were eligible to be included. These studies combined structural and

SUBMITTER: Scheepens DS 

PROVIDER: S-EPMC7283615 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature