Electrospun Biomaterials in the Treatment and Prevention of Scars in Skin Wound Healing.

ABSTRACT: Electrospinning is a promising method for the rapid and cost-effective production of nanofibers from a wide variety of polymers given the high surface area morphology of these nanofibers, they make excellent wound dressings, and so have significant potential in the prevention and treatment of scars. Wound healing and the resulting scar formation are exceptionally well-characterized on a molecular and cellular level. Despite this, novel effective anti-scarring treatments which exploit this knowledge are still clinically absent. As the process of electrospinning can produce fibers from a variety of polymers, the treatment avenues for scars are vast, with therapeutic potential in choice of polymers, drug incorporation, and cell-seeded scaffolds. It is essential to show the new advances in thi

SUBMITTER: Mulholland EJ 

PROVIDER: S-EPMC7283777 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature