Molecular Aspects and Future Perspectives of Cytokine-Based Anti-cancer Immunotherapy.

ABSTRACT: Cytokine-based immunotherapy is a promising field in the cancer treatment, since cytokines, as proteins of the immune system, are able to modulate the host immune response toward cancer cell, as well as directly induce tumor cell death. Since a low dose monotherapy with some cytokines has no significant therapeutic results and a high dose treatment leads to a number of side effects caused by the pleiotropic effect of cytokines, the problem of understanding the influence of cytokines on the immune cells involved in the pro- and anti-tumor immune response remains a pressing one. Immune system cells carry CD makers on their surface which can be used to identify various populations of cells of the immune system that play different roles in pro- and anti-tumor immune responses. This review disc

SUBMITTER: Chulpanova DS 

PROVIDER: S-EPMC7283917 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature