CASC15 polymorphisms are correlated with cervical cancer susceptibility in Chinese women.

ABSTRACT:

Background

Cervical cancer is a frequent, common cancer in women, and causes high cancer-related deaths among women in our world. Accumulating studies provided an important evidence for long noncoding RNA (lncRNA) polymorphisms in the susceptibility of various cancer. Here, we recruited 494 cervical cancer cases and 504 unrelated controls to assess the relationship between CASC15 (OMIM# 616610) polymorphisms and cervical cancer susceptibility.

Methods

Agena MassARRAY platform was conducted to genotype CASC15 polymorphisms. Odds ratios (ORs) and 95% confidence intervals (CIs) were analyzed through logistic regression to adjust for confounding factors, such as age and gender.

Results

Our study suggested that rs12212674 (NC_000006.12:g.22086845T>A) "A" allele was signifi

SUBMITTER: Gao Z 

PROVIDER: S-EPMC7284034 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature