Two Distinct Types of Eye-Head Coupling in Freely Moving Mice.

ABSTRACT: Animals actively interact with their environment to gather sensory information. There is conflicting evidence about how mice use vision to sample their environment. During head restraint, mice make rapid eye movements coupled between the eyes, similar to conjugate saccadic eye movements in humans. However, when mice are free to move their heads, eye movements are more complex and often non-conjugate, with the eyes moving in opposite directions. We combined head and eye tracking in freely moving mice and found both observations are explained by two eye-head coupling types, associated with vestibular mechanisms. The first type comprised non-conjugate eye movements, which compensate for head tilt changes to maintain a similar visual field relative to the horizontal ground plane. The second ty

SUBMITTER: Meyer AF 

PROVIDER: S-EPMC7284311 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature