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The Impact of Human Milk on Necrotizing Enterocolitis: A Systematic Review and Meta-Analysis.


ABSTRACT: Premature infants receiving breastfeed have a lower incidence of NEC than those fed preterm formula. This study aimed: (1) to update a systematic review and meta-analyses to evaluate the relationship between feeding and necrotizing enterocolitis (NEC) in low weight premature infants; (2) to conduct meta-regression analyses by subgroups; (3) to describe geographical distribution of milk banks in the world. Papers included in the meta-analysis were updated as of June 2019. Relative risks were used as a measure of effect size. Random effect models were used to account for different sources of variation among studies. For milk banks, the data reviewed by the literature were integrated with the information collected from countries' institutional sites and milk bank networks. Thirty-two papers w

SUBMITTER: Altobelli E 

PROVIDER: S-EPMC7284425 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature