Coffee Consumption and C-Reactive Protein Levels: A Systematic Review and Meta-Analysis.

ABSTRACT: Coffee contains bioactive compounds with anti-inflammatory properties, and its consumption may reduce c-reactive protein (CRP) levels, a biomarker of chronic inflammation. A previous meta-analysis reported no overall association between blood CRP level and coffee consumption by modeling the coffee consumption in categories, with substantial heterogeneity. However, the coffee cup volume was not considered. We conducted a systematic review and dose-response meta-analysis investigating the association between coffee consumption and CRP levels reported in previous observational studies. A dose-response meta-analysis was conducted by mixed-effects meta-regression models using the volume of coffee consumed as metric. Eleven studies from three continents were identified using the PubMed database,

SUBMITTER: Moua ED 

PROVIDER: S-EPMC7285227 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature