Bisphenol A shapes children's brain and behavior: towards an integrated neurotoxicity assessment including human data.

ABSTRACT: Concerns about the effects of bisphenol A (BPA) on human brain and behavior are not novel; however, Grohs and colleagues have contributed groundbreaking data on this topic in a recent issue of Environmental Health. For the first time, associations were reported between prenatal BPA exposure and differences in children's brain microstructure, which appeared to mediate the association between this exposure and children's behavioral symptoms. Findings in numerous previous mother-child cohorts have pointed in a similar worrying direction, linking higher BPA exposure during pregnancy to more behavioral problems throughout childhood as assessed by neuropsychological questionnaires. Notwithstanding, this body of work has not been adequately considered in risk assessment. From a toxicological pers

SUBMITTER: Mustieles V 

PROVIDER: S-EPMC7285610 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature