Stage 1 acute kidney injury is independently associated with infection following cardiac surgery.

ABSTRACT:

Objectives

Severe acute kidney injury (AKI) is a known risk factor for infection and mortality. However, whether stage 1 AKI is a risk factor for infection has not been evaluated in adults. We hypothesized that stage 1 AKI following cardiac surgery would independently associate with infection and mortality.

Methods

In this retrospective propensity score-matched study, we evaluated 1620 adult patients who underwent nonemergent cardiac surgery at the University of Colorado Hospital from 2011 to 2017. Patients who developed stage 1 AKI by Kidney Disease Improving Global Outcomes creatinine criteria within 72 hours of surgery were matched to patients who did not develop AKI. The primary outcome was an infection, defined as a new surgical-site infection, positive blood or urine c

SUBMITTER: Griffin BR 

PROVIDER: S-EPMC7285820 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature