Efficacy and safety of CT-guided ¹²⁵I brachytherapy in elderly patients with non-small cell lung cancer.

ABSTRACT: Non-small cell lung cancer (NSCLC) has become the most common cancer type and the leading cause of cancer-associated mortality worldwide. The aim of the present retrospective study was to evaluate the efficacy and safety of computed tomography (CT)-guided ¹²⁵I brachytherapy alone in elderly patients with NSCLC. A total of 26 elderly patients with NSCLC stage I-III who had an inoperable lesion or progressive disease following radio-chemotherapy were treated with CT-guided ¹²⁵I seed implantation for lung lesions and included in the present study. The prescribed dose of ¹²⁵I brachytherapy was 80-140 Gy, and dosimetric verification was performed immediately after the procedure. The response rate (RR) and local control rate (LCR) were analyzed according to the R

SUBMITTER: Zhao J 

PROVIDER: S-EPMC7286004 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature