Lamina cribrosa pore movement during acute intraocular pressure rise.

ABSTRACT:

Purpose

To assess changes in the position of lamina cribrosa pores (LCPs) induced by acute intraocular pressure (IOP) elevation.

Methods

A prospective observational study. Acute angle-closure suspects who underwent the 2-hour dark room prone provocative test (DRPPT) were included. At baseline and within 5 min after the DRPPT end, tonometry, fundus photography and optical coherence tomography were performed. Optic disc photos taken before and after the DRPPT were aligned and moving distance of each visible LCP was measured (LCPMD).

Results

38 eyes from 27 participants (age: 52.5±10.8 years) were included. The IOP rose from 16.7±3.2 mm Hg at baseline to 23.9±4.3 mm Hg at the DRPPT end. The mean lateral LCPMD was 28.1±14.6 µm (range: 5.0-77.2 µm), which increased with hi

SUBMITTER: Wang YX 

PROVIDER: S-EPMC7286041 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature